Katonga Wildlife Reserve offers Uganda wildlife safaris in western Uganda, along the banks of the Katonga River. The reserve was established in 1998 and has approximately 211 square kilometers (81 sq. mi). Many of the species of plants and animals in the reserve are unique to its wetland environment.The reserve is named after the Katonga River, which flows from Lake Victoria in the east to Lake George in the west.

The reserve is located in the Ibanda and Kamwenge Districts in western Uganda. In Kamwenge, it borders with the Biguli sub county and part of the Mpara sub county in Kyenjojo District. The reserve is approximately 200 kilometers (120 mi), by road, west of Kampala, Uganda's capital city.

The vegetation of the reserve is mixed Savannah with acacia scrub land or woodlands. A large portion of the reserve is either permanent or seasonal wetlands. There are also pockets of Riverine and tropical forest.

Katonga wildlife reserve has over 150 bird species and over 40 wildlife species which include; colobus monkeys, sitatunga, warthog, elephant, water buck, reed buck, bush buck and river otter. This Reserve is best explored on foot or by river canoe with the guide and it’s managed by Uganda Wildlife Authority.